Phen24 Review: why do you need to know about this product?

“The greatest wealth is health” –Anonymous

Name Phen24.

Website: phen24.co.uk

Review Topic: Nutritional Supplement, Weight Loss.

Price: 1 BOX (30 Day pills and 60 Night pills): Retail price:  £59.99.  Now £49.99. Savings: £10.00

Owner: WOLFSON BERG LIMITED.

The place to buy: phen24.co.uk

 

Phen24 is a powerful product for weight loss of 24/24 hours. It is a two-bottle presentation, Phen24 day and Phen24 night. This product has been exclusively designed with the purpose of having you lose weight as a 24-hour working process.

Phen24 successfully functions as a complement supporting your decisive weight loss resolution. When combined with healthy eating and regular physical activities, Phen24 can greatly fulfill your desire of losing weight, accompanied with two more important benefits: a high reduction of your cravings and a significant increase of deeper sleep time. You can see my post about Proteins.

Phen24 includes a composition whose natural ingredients are ideal for both women and men, including vegetarians and vegans. By consuming this product, you are supplied with a whole solution to your weight loss.

Phen24 contains compounds that help you not only improve your weight loss but also render a quality sleep as a key point for weight loss. Lack of sleep in humans can compromise the preservation of fat-free body mass during times of energy intake reduction for weight loss (1).

In overweight and obese women, studies have demonstrated that sleep quality and quantity can influence weight loss. Reduced sleep length augments time available for snacking especially carbohydrate consumption (2).

Inadequate sleep alters neuroendocrine appetite control, reducing leptin and increasing ghrelin concentrations. These are hormones promoting satiety and hunger, respectively. This inadequacy decreases insulin sensitivity and increases evening concentrations of cortisol. Consequently, sleep losses increase obesity risk (3, 4).

You can order Phen24 now

Phen24 Dayhttps://weightliability.com/phen24-review-why-do-you-need-to-know-about-this-product/

Phen24 Day is composed of ingredients to boost your metabolism, speed up your weight loss, supply you with more energy, burn more calories, improve your digestion, and regulate your thyroid.

Phen24 Day ingredients

  • Caffeine.
  • Guarana extract.
  • Cayenne pepper.
  • Phenylalanine.
  • Iodine.
  • Manganese.
  • Zinc citrate.
  • Copper sulfate.

Caffeine

It has properties that stimulate arousal, alertness, energy, and elevated mood. Caffeine is added to a great variety of food, drinks, and other products.

Caffeine Consumption is rather safe in general for healthy adults. Some cases are known in which caffeine intake has to be avoided due to health conditions like impairments in cardiovascular function and sleep.

The ingested caffeine is soluble in water as well in lipids and crosses the blood-brain barrier. It can be found in all body fluids. It has been shown that caffeine intake might foster weight, body mass index and body fat reduction (5).

Guarana extract

This natural product provokes stimulant effects based on its caffeine content, four times higher than in coffee. Guarana also contains other natural chemicals that heighten its stimulant effects. Composed of natural phenols: catechin and epicatechin, Guarana bears cardiac stimulants such as theobromine, theophylline, and tannin (6).

Guarana ingestion increases resistance to LDL oxidation. The high content of polyphenolic compounds can prevent atherogenesis. It increases basal energy expenditure and generates positive effects on weight loss and lipid metabolism. This ingestion produces a cardioprotective effect by inhibiting platelet aggregation, diminishing metabolic syndrome, hypertension prevalence, and lower cholesterol (6).

Cayenne pepper

The phytochemical responsible for the spiciness of the peppers is capsaicin having the potential to modulate metabolism. Effectively, capsaicin can modestly enhance energy spending, augment fat oxidation, diminish appetite, and, to such a degree, conduct to weight control (7).

Phenylalanine

The Phenylalanine is an essential aromatic amino acid in humans, provided by food. It is an appetite suppressant by mediating the intestinal hormone release called cholecystokinin. This hormone, in turn, sends a signal to the brain to feel satiated after food ingestion (8).

Iodine

Iodine is a fundamental component of the thyroid hormones, triiodothyronine (T3), and thyroxine (T4). These hormones are required for normal metabolic processes.

The thyroid hormones are produced by the thyroid gland. These hormones regulate the basal metabolic rate, thermogenesis, and body metabolism in starved and fed states.

There are clinical manifestations of thyroid hormone changes related to metabolism:

–           Deficiency: weight gain, decreased synthesis and degradation of lipids, cold intolerance, low resting metabolic rate (RMR), decreased appetite, flat glucose tolerance curve with delayed insulin response; reduced body temperature, increased insulin sensitivity.

–           Excess: increased synthesis and degradation of lipids and proteins, increased RMR, and appetite; weight loss; decreased glucose tolerance (9).

People adhering to restricted diets in a weight-loss program may be at risk for mild to moderate iodine deficiency.

Manganese

Manganese is indispensable for blood sugar regulation and cellular energy, reproduction, proper immune function, blood coagulation, hemostasis, bone growth, and digestion.

An insufficient diet in manganese produces poor bone formation and skeletal defects, impaired growth, altered lipid and carbohydrate metabolism, and abnormal glucose tolerance (10).

Zinc citrate

In all living organisms, zinc is an essential micronutrient, crucial for physical development, metabolism of fats, carbohydrates, proteins, and growth. This micronutrient carries out regulatory functions, signal transduction, and cellular control. Its activation or effect is indispensable for the performance or functioning of the immune system (11).

Copper sulfate

Copper is an essential metal functioning in redox balance, iron mobilization, lipid metabolism, and many other critical processes in the body.

The copper insufficiency is implicated in or connected with common diseases like metabolic syndrome, ischemic heart disease, and obesity. It is a potential etiologic factor in diseases characterized by disrupted lipid metabolism as non-alcoholic fatty liver disease. Sub-optimal levels of copper promote dyslipidemia and increase oxidative stress (12).

Phen24 Nighthttps://weightliability.com/phen24-review-why-do-you-need-to-know-about-this-product/

This supplement works well during daytime and its effects still keep helping you with your weight loss all night long. This full-time outcome assures you sufficient sleep hours of excellent quality. Doing so, your metabolism remains engaged at night and your weight loss process goes on once initiated earlier during the day.

Cortisol known as the stress hormone is a key factor that can sabotage your weight loss. This hormone is released in a diurnal manner, early in the morning to ease arousal occurring, at its highest level, at about 8 a.m. It declines slightly in the evening and during the early sleep phase (13).

Throughout the day, cortisol sustains blood glucose and provides energy to an actively functioning brain and neuromuscular system by suppressing nonvital organ systems. It protects nerves and tissues from damages linked to inflammation (13).

In the stress-response, there is an increase in cortisol secretion; but in the long range, prolonged secretion of it can have crippling effects, psychologically and physically (13).

Cortisol supports central fat deposition/discharge, a reduction in the adipostatic signal leptin and a rise in the orexogenic signal ghrelin, inducing increased appetite and food intake, contributing to obesity. It can also precipitate thyroid storm (14).

Researches provide evidence that chronic exposure to stress, overnutrition, and sleep deprivation, potentially lead to the increased incidence and prevalence of metabolic disorders like Type 2 Diabetes and obesity (15).

Phen24 Night ingredients

  • Glucomannan.
  • Chrome picolinate.
  • Biotin.
  • Choline bitartrate.
  • Molybdenum (sodium molybdate).
  • Pantothenic acid (Vitamin B5).
  • Thiamine (Vitamin B1).
  • HCl pyridoxine (Vitamin B6).
  • Green tea extract.
  • Ascorbic acid (Vitamin C).
  • Griffonia extract.
  • Hop extract.

Glucomannan

Glucomannan is a key component of Phen24 Night, a soluble, fermentable, and highly viscous dietary fiber derived from the root of the konjac plant. It promotes not only weight loss in overweight and obese persons, satiety and fecal energy loss, but also improves lipid and lipoprotein parameters and glycemic status (16).

Chrome picolinate

Chromium is an essential trace element and a nutritional supplement. In young women, it reduces food intake, hunger; and carbohydrates, fast foods, high-fat foods, and sweet cravings over time. This element tends to decrease body weight. Chromium picolinate may influence physiological satiety signals and sustain satiety levels during caloric restriction periods (17).

The supplementation with chromium picolinate produces a favorable effect on glycemic control in patients with poorly controlled Type 2 Diabetes Mellitus, without affecting the lipid profile (18).

Biotin

Biotin is a water-soluble vitamin, a coenzyme for five carboxylases in humans. Biotin can affect chromatin structure and mediate gene regulation. The deficiency produces fatty acid profile alterations in liver, skin, and serum. It is needed to metabolize fats, carbohydrates, and proteins. That deficiency is associated with increased abundance of odd-chain fatty acids abnormalities in fatty acid composition (19).

Choline bitartrate

The amine choline is a vitamin B-complex family member, naturally produced by the body to burn fat. It breaks fat down to be used as an energy source. Choline’s metabolism of fats is linked to a greater level of satiety, leading to reduced consumption of calories. This process results in overall weight loss. Choline supplementation reduces leptin levels, body fat, and body mass index. Choline functions also as an antioxidant. (20).

Molybdenum (sodium molybdate)

Molybdenum is required for the activity of at least seven enzymes in your body, and numerous body systems rely on these enzymes as support.

This ingredient is mandatory in the activity of the enzyme called sulfite oxidase (SO), which takes one form of sulfur (sulfite) and makes it into another form (sulfate) for keeping sulfur moving around in your body.

Molybdenum backs up liver detoxification, connects tissue development, antioxidant assistance, tissue development, and other aspects of your health due to the general importance of sulfur balance throughout your body.

Molybdenum, a cofactor for the enzyme aldehyde oxidase, is critical through the first phase of liver cell detoxification, called phase I.

A molybdenum deficiency would impair the functions of these enzymes preventing the body from processing amino acids that contain sulfur. It balances uric acid levels, preserves nitric oxide levels and facilitates circulation. (21).

Pantothenic acid (Vitamin B5)

Pantothenic acid, a vitamin, also known as Vitamin B5, is an essential nutrient and functions as a coenzyme A component and phosphopantetheine involved in fatty acid metabolism (22).

Thiamine (Vitamin B1)

Thiamine or Vitamin B1 is one of the eight essential B vitamins that help the body transform carbohydrates, fat, and protein into energy (23).

HCl pyridoxine (Vitamin B6)

Vitamin B6 is water-soluble, a cofactor in more than 100 enzyme reactions, including amino acid metabolism, particularly homocysteine; carbohydrate metabolism, comprising glycogenolysis and gluconeogenesis; and lipid metabolism (23).

Green tea extract

Green tea contains catechins (antioxidants) and caffeine. Epigallocatechin gallate (EGCG) is the most common catechin in green tea, and popular for boosting metabolism (24).

Ascorbic acid (Vitamin C)

Vitamin C is water-soluble. Ascorbic acid as an antioxidant generates many beneficial effects on obesity: a) regulate the release of the glucocorticoids of adrenal glands, leading to an improvement in hyperglycemia and decrease glycosylation in obese diabetic models, module adipocyte lipolysis; b) inhibit glucose metabolism and leptin secretion on isolated adipocytes; c) reduce the inflammatory response (25).

Griffonia extract

Griffonia simplicifolia Baill seed extract is rich in 5-hydroxy-l-tryptophan (5-HTP), a direct precursor in the synthesis of serotonin (5-HT) that exerts an anxiolytic-like effect in improving your sleep quality and increasing the feeling of satiety (26).

Hop extract

The matured hop bitter acids (MHBA) of oxidized hops reduce body fat, predominantly the abdominal visceral fat (27).

Pros’ Phen24

  • It has been designed to work in your weight loss process around the clock to assure you succeed in achieving your weight loss decision.
  • It contains compounds that increase your body metabolic rate to burn fat twenty-four hours long.
  • It promotes relaxation to help you have better sleep quality and quantity and avoid weight gain.
  • It diminishes your cravings at night.
  • It increases your energy during the day.
  • Phen24 Day and Phen24 Night are 100% vegetarian and vegan.
  • It encourages the fat breakdown throughout the night.
  • Its shipping is free worldwide.

Cons’ Phen24

  • Caffeine causes nervousness, insomnia, nausea and increased blood pressure in some individuals.
  • Phen24 Night can cause insomnia in certain people due to its content of green tea. To avoid such an effect, it is important to assure that all persons know Phen24 Night has to be taken early in the evening, not at bedtime.
  • The exact quantity of each component in Phen24 is neither specified nor its possible side effects.

Who is Phen24 recommended for?

Phen24 can be consumed by women and men.

If you have some specific medical conditions or you are under medication, you should talk to your physician before initiating your supplementation with Phen24.

According to the manufacturer, more than 90,000 people worldwide have reached their ideal weight with Phen24.

Phen24 is a safe product. In case you are under 18 years, are nursing or pregnant, or if you have any of these health conditions, avoid taking it:

  • Feeling Depression and taking antidepressants.
  • Diabetes.
  • Endocrine Diseases.
  • Autoimmune Diseases.
  • Hypertrophy or Prostate Cancer.
  • Liver Disease.
  • Kidney Disease.
  • Testicular Cancer.
  • Breast Cancer.

How Much Does Phen24 Cost?

 1 BOX (30 Day pills and 60 Night pills): Retail: £59.99. 

Now is £49.99. Savings: £10.00

 

2 BOXES + 1 FREE

Retail: £149.99. Now is £99.99. 

Savings: £50.00

 

 3 BOXES + 2 FREE + FREE ADVANA CLEANSE

Retail: £249.75. Now is £149.99

Savings: £100.00

 

https://weightliability.com/phen24-review-why-do-you-need-to-know-about-this-product/

You can order Phen24 now

If you want or strive for long-term benefits produced by of Phen24 guaranteed, and you also plan in advance, the manufacturer recommends your buying three Phen24 boxes. By doing so, you automatically receive TWO boxes FREE.

Guaranteed results or your money back.

How can you take Phen24?

To take Phen24 is easy enough.

Phen24 Day: consume one capsule in the morning with your breakfast.

Phen24 Night: consume one capsule 15 minutes before your dinner with 1 or 2 glasses of water.

Phen24, a nutritional supplement working day and night, generates real results for you by sticking to your healthy eating and regular physical training.

Phen24’s Manufacturer

Phen24 is supplied and manufactured by WOLFSON BERG LIMITED, a trusted brand and proud leader in the supplement industry for over a decade.

It is located at:

WOLFSON BERG LIMITED

141 Avenue Félix Faure

75015 Paris

France

Phen24 support

The product specialist and customer service managers are available to help you clear up any of your questions, doubts and/or concerns.

On the website, “Customer Service” section, you have, at your disposal, a drop-down menu where you find specific and appropriate services. The business hours are from Monday through Friday, 9 am – 6 pm. Questions received after office hours and/or on weekends will be processed the following business day.

Here you are the toll-free number during the opening hours:

33 176 753 338. If preferred, you can count on its chat services.

My Conclusive Viewpoint about Phen24

Phen24 is a nutritional supplement whose ingredients can help you effectively lose weight, through boosting your metabolism, burning fat, improving your sleep quality and quantity. Phen24 is an ally of your weight loss all day long with a great ingredients combination.

The manufacturer provides great support to its customers, offers, price reductions, and includes guarantees. By being fully encouraging and understanding, the manufacturer openly facilitates your product acquisition.

Keep in mind that only by creating or setting healthy eating habits, exercising and developing a creative lifestyle, you can steadily achieve your desired weight loss and firmly optimize your life process with Phen24 supplementation as a valuable product.

Phen24 is a LEGIT product and you will be supplied with any required or needed information by contacting the manufacturer.

You can order Phen24 now

I would appreciate your comments related to your personal experience or concerns you have about Phen24.

 

References

1. Arlet V. Nedeltcheva, Jennifer M. Kilkus, Jacqueline Imperial, Dale A. Schoeller, and Plamen D. Penev. Insufficient sleep undermines dietary efforts to reduce adiposity. Ann Intern Med. 2010 October 5; 153(7): 435–441. doi:10.1059/0003-4819-153-7-201010050-00006.

2. Cynthia A. Thomson, Kelly L. Morrow, Shirley W. Flatt, Betsy C. Wertheim, Michelle M. Perfect, Jennifer J. Ravia, Nancy E. Sherwood, Njeri Karanja, and Cheryl L. Rock. Relationship between Sleep Quality and Quantity and Weight Loss in Women Participating in a Weight-Loss Intervention Trial. Obesity. 2012 July; 20(7): 1419–1425. doi:10.1038/oby.2012.62.

3. Knutson K. L, and Van Cauter E. Associations between sleep loss and increased risk of obesity and diabetes. Ann N Y Acad Sci. 2008. 1129:287–304. doi: 10.1196/annals.1417.033.

4. Guglielmo Beccutia, and Silvana Pannaina. Sleep and obesity. Curr Opin Clin Nutr Metab Care. 2011. July; 14 (4): 402–412. doi:10.1097/MCO.0b013e3283479109.

5. Reza Tabrizi, Parvane Saneei, Kamran B Lankarani Icon, Maryam Akbari, Fariba Kolahdooz, Ahmad Esmaillzadeh, Somayyeh Nadi-Ravandi, Majid Mazoochi, and Zatollah Asemi. The effects of caffeine intake on weight loss: a systematic review and dose-response meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2018 Oct 18:1-9. doi: 10.1080/10408398.2018.1507996.

6. Rafael de Lima Portella, Rômulo Pillon Barcelos, Edovando José Flores da Rosa, Euler Esteves Ribeiro, Ivana Beatrice Mânica da Cruz, Leila Suleiman, and Felix Alexandre Antunes Soares. Guaraná (Paullinia cupana Kunth) effects on LDL oxidation in elderly people: an in vitro and in vivo study. Lipids in Health and Disease 2013, 12:12.

7. Mark F McCarty, James J DiNicolantonio, James H O’Keefe. Capsaicin may have important potential for promoting vascular and metabolic health. Open Heart 2015;2:e000262. doi:10.1136/openhrt-2015-000262.

8. Ballinger A. B., and Clark M. L. L-phenylalanine release cholecystokinin (CCK) and is associated with reduced food intake in humans: evidence for a physiological role of CCK in control of eating. Metabolism. 1994. 43(6):735-8.

9. Nussey S, Whitehead S. Endocrinology: An Integrated Approach. Oxford: BIOS Scientific Publishers; 2001.

10. Michael Aschner, and Keith Erikson. Manganese.  Adv Nutr 2017;8:520–1; doi:10.3945/an.117.015305.

11. Wolfgang Maret. Zinc Biochemistry: From a Single Zinc Enzyme to a Key Element of Life. Adv. Nutr. 4: 82–91, 2013; doi:10.3945/an.112.003038.

12. Austin Morrell, Savannah Tallino, Lei Yu, and Jason L. Burkhead. The role of insufficient copper in lipid synthesis and fatty-liver disease. IUBMB Life. 2017 Apri; 69(4): 263–270. doi:10.1002/iub.1613.

13. Kara E. Hannibal, and Mark D. Bishop. Chronic Stress, Cortisol Dysfunction, and Pain: A Psychoneuroendocrine Rationale for Stress Management in Pain Rehabilitation. Phys Ther. 2014 Dec; 94(12): 1816–1825. doi: 10.2522/ptj.20130597.

14. Salam Ranabir and K. Reetu. Stress and hormones. Indian J Endocrinol Metab. 2011 Jan-Mar; 15(1): 18–22. doi: 10.4103/2230-8210.77573.

15. Camila Hirotsun, Sergio Tufik, and Monica Levy Andersen. Interactions between sleep, stress, and metabolism: From physiological to pathological conditions. Sleep Science. Volume 8, Issue 3, November 2015, Pages 143-152. https://doi.org/10.1016/j.slsci.2015.09.002.

16. Keithley J, Swanson B. Glucomannan and obesity: a critical review. Alternative Therapies in Health and Medicine. 2005 Nov-Dec; 11(6):30-4.

17. Stephen D. Anton, Christopher D. Morrison, William T. Cefalu, Corby K. Martin, Sandra Coulon, Paula Geiselman, Hongmei Han, Christy L. White, D and Donald A. Williamson. Effects of Chromium Picolinate on Food Intake and Satiety. Diabetes Technology & Therapeutics. Volume 10, Number 5, 2008. DOI: 10.1089/dia.2007.0292.

18. Paiva A. N., Lima J. G., Medeiros A. C., Figueiredo H. A., Andrade R. L., Ururahy M. A., Rezende A. A., Brandão-Neto J., Almeida M. Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study. J Trace Elem Med Biol. 2015 Oct;32:66-72. doi: 10.1016/j.jtemb.2015.05.006.

19. Janos Zempleni, Subhashinee S.K. Wijeratne, and Yousef I. Hassan. Biotin. Biofactors. 2009; 35(1): 36–46. doi:10.1002/biof.8.

20. Gehan Elsawy, Osama Abdelrahman, and Amr Hamza. Effect of Choline Supplementation on Rapid Weight Loss and Biochemical Variables Among Female Taekwondo and Judo Athletes. Journal of Human Kinetics. 2014 Mar 27; 40: 77–82. doi: 10.2478/hukin-2014-0009.

21. Eudeamon. Molybdenum (Sodium Molybdate).

22. David O. Kennedy. B Vitamins and the Brain: Mechanisms, Dose and Efficacy -A Review. Nutrients 2016, 8, 68; doi:10.3390/nu8020068.

23. Kenneth Osiezagha, Shahid Ali, C. Freeman, Narviar C. Barker, Shagufta Jabeen, Sarbani Maitra, Yetunde Olagbemiro, William Richie, and Rahn K. Bailey. Thiamine Deficiency and Delirium. Innov Clin Neurosci. 2013; 10(4):26–32.

24. Hursel R., Viechtbauer W., and Westerterp-Plantenga M. S. The effects of green tea on weight loss and weight maintenance: a meta-analysis. Int J Obes. 2009 Sep;33(9):956-61. doi: 10.1038/ijo.2009.135. Epub 2009 Jul 14.

25. Diego Fernando Garcia-Diaz, Patricia López-Legarrea, Pablo Quintero and Jose Alfredo-Martinez. Vitamin C in treatment and/or prevention of obesity. 2014. J Nutr Sci Vitaminol, 60, 367-379.

26. Rondanelli M., Opizzi A., Faliva M., Bucci M., and Perna S. Relationship between the absorption of 5-hydroxytryptophan from an integrated diet, by means of Griffonia simplicifolia extract, and the effect on satiety in overweight females after oral spray administration. Eat Weight Disord. 2012 Mar; 17(1):e22-8. doi: 10.3275/8165.

27. Yumie Morimoto-Kobayashi, Kazuaki Ohara, Hiroshi Ashigai, Tomoka Kanaya, Kumiko Koizumi,Fumitoshi Manabe, Yuji Kaneko, Yoshimasa Taniguchi, Mikio Katayama, Yasuyuki Kowatari, and Sumio Kondo. Matured hop extract reduces body fat in healthy overweight humans: a randomized, double-blind, placebo-controlled parallel group study. Nutrition Journal (2016) 15:25. DOI 10.1186/s12937-016-0144-2.

 

 

 

 

 

 

 

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